An emphasis on transitional research
The medical aim of our projects is to improve the physiopathological understanding of sensori- and cognitivo-motor disabilities, as well as their diagnostic, quantitative evaluation, and rehabilitation. Motor disabilities in adults and children are very frequent and lead to major loss of autonomy. The studies we plan to develop concern patients with damage to the neural network which subserves motor functions and their interactions with sensory and cognitive functions. Special emphasis will be put on lesions involving the posterior parietal cortex, the frontal cortex, the occipital cortex, the basal ganglia and the cerebellum. Damage to this network is present, to varying extent, in several pathologies. It can happen after strokes, which are the first cause of neurological disability in the adult. Such focal damage to the nervous system provides insight into the dissociations of function within neural networks. It is also present in degenerative diseases such as Parkinson's disease, which leads to a dysfunction of the basal ganglia and its frontal connections. The recent development of a surgical treatment of this disease using deep brain stimulation provides new electrophysiological insight into motor disorders. Developing research in children with cerebral-palsy, in addition to our current research in adults, is a new objective of the laboratory, further stimulated by the recent opening of a children hospital (HFME) nearby.
- Multiple Sclerosis
- Optic Ataxia
- Unilateral Neglect